Ryan Mehl, PhD
Full Professor
Director, Unnatural Protein Facility
ryan.mehl at oregonstate.edu
Bio:
I got hooked on encoding new amino acids in 2001 and ever since my research has focused on developing GCE and using the technology study protein structure and function. I received organic synthesis and mechanistic enzymology training under Tadhg Begley at Cornell University and chemical biology/protein engineering training under Peter Schultz at Scripps Research Institute. In 2011, I relocated to Oregon State University, to expand my research program and created the Unnatural Protein Facility dedicated to facilitating the use of GCE.
 
Research:
My research can be found in the research tab here
Rick Cooley, PhD
Research Assistant Professor
cooleyr at oregonstate.edu
Bio:
After graduate training in biochemistry and structural biology under Dan Arp and Andy Karplus at Oregon State, I worked with Ryan Mehl to set up the first Unnatural Protein Facility here at OSU before continuing to a second post-doc with Holger Sondermann at Cornell University. Still captivated by the potential of Genetic Code Expansion technology, I moved back to OSU to continue working at the UP Facility as its manager and to start my faculty career in GCE research and structural biology.
 
Research:
My research centers on using, improving and creating new GCE technologies to study how protein structure and function are regulated by post-translational modifications.
Savanna Avila-Crump
Unnatural Protein Facility Coordinator
avilacrs at oregonstate.edu
Bio:
As the Unnatural Protein Facility coordinator I facilitate use of genetic code expansion for scientists who wish to use this technology in their own research. This involves workshop-style education about genetic code expansion, individual training and consultation, and large-scale production of ncAA labeled proteins for academic and industrial research groups.
 
Reasearch:
Outside of my facility duties, I am working on a couple of ongoing research projects under Ryan Mehl and Rick Cooley. My main research project aims to engineer an additional orthogonal system so that we can incorporate multiple ncAA into proteins.
Subhashis Jana, PhD
Postdoctoral Scientist
janasu at oregonstate.edu
 
Riley Bednar
Graduate Student
bednarr at oregonstate.edu
Bio:
 
Research:
 
Phillip Zhu
Graduate Student
zhuph at oregonstate.edu
 
 
Elise Van Fossen
Graduate Student
vanfosse at oregonstate.edu
Bio:

I’m originally from Long Beach, CA and completed my undergraduate work and Masters work at California State University, Long Beach. I love lunch, my house plants and am a mediocre free-style rapper. 

Research:
I am currently studying oxidative stress-related post-translational modifications in proteins using genetic code expansion and engineered nanobodies.
Alex Eddins
Graduate Student
eddinsa at oregonstate.edu
 
Grace Galles
Researcher
grace-galles at uiowa.edu
Bio:
I’m a recent graduate from the University of Iowa working in conjunction with both UIowa and Oregon State to develop genetic code expansion tools to be used for research in ion channel structure and function.  Outside of lab I spend time with my plants, play rugby, and am a slightly-below-average crocheter.
 
Research:
My research involves the development of new pyrrolysine synthetases for fluorinated aromatics to be used to probe cation-pi interactions and fluorophores for following conformational changes in ion channels in eukaryotic systems.
Ilana Gottfried-Lee
Undergraduate Researcher
gottfrii at oregonstate.edu
 
 
Joshua Griffis
Undergraduate Researcher
griffijo at oregonstate.edu
Bio:
I am in my first year of my Biochemistry and Molecular Biology degree here at OSU. Prior to coming here, I spent six years in the United States Navy operating nuclear reactors but I'm excited to switch gears and learn how life works. 
 
Research:
I am just getting started on selecting for a better tRNA to be used for the insertion of phosphoserine as a ncAA in proteins. This would provide a better tool for scientist who wish to study the effects of phosphoserine incorporation in proteins.